Recent advances on biologically active coumarin-based hybrid compounds

dc.authoridPoyraz, Samet/0000-0002-9698-7959
dc.authoridErsatir, Mehmet/0000-0003-1077-0626
dc.contributor.authorYildirim, Metin
dc.contributor.authorPoyraz, Samet
dc.contributor.authorErsatir, Mehmet
dc.date.accessioned2025-03-17T12:27:39Z
dc.date.available2025-03-17T12:27:39Z
dc.date.issued2023
dc.departmentTarsus Üniversitesi
dc.description.abstractCoumarin hybrids have been designed and synthesized as an important new strategy in the field of medicinal chemistry. Coumarin core has been shown to form various compounds to combat several diseases including microbial, cancer, inflammatory, and neurodegenerative disorders. Recently, a number of coumarin-based drugs (e.g., coumadin, acenocoumarol, dicoumarol, phenprocoumon, and novobiocin) have been FDA-approved and are in the clinic, and several coumarin-containing compounds are in clinical trials. Our group classified coumarin-based hybrid compounds into groups showing shared biological activities and discussed their potential therapeutic targets.
dc.identifier.doi10.1007/s00044-023-03025-x
dc.identifier.endpage642
dc.identifier.issn1054-2523
dc.identifier.issn1554-8120
dc.identifier.issue4
dc.identifier.scopus2-s2.0-85147682576
dc.identifier.scopusqualityQ1
dc.identifier.startpage617
dc.identifier.urihttps://doi.org/10.1007/s00044-023-03025-x
dc.identifier.urihttps://hdl.handle.net/20.500.13099/2381
dc.identifier.volume32
dc.identifier.wosWOS:000931961400001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSpringer Birkhauser
dc.relation.ispartofMedicinal Chemistry Research
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250316
dc.subjectCoumarin hybrids
dc.subjectCoumarin sulfonamide hybrids
dc.subjectCoumarin-triazole hybrids
dc.subjectCoumarin thiazole hybrids
dc.subjectCoumarin-chalcone hybrids
dc.subjectCoumarin-imidazole hybrids
dc.titleRecent advances on biologically active coumarin-based hybrid compounds
dc.typeReview

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