Recent advances on biologically active coumarin-based hybrid compounds
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Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer Birkhauser
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Coumarin hybrids have been designed and synthesized as an important new strategy in the field of medicinal chemistry. Coumarin core has been shown to form various compounds to combat several diseases including microbial, cancer, inflammatory, and neurodegenerative disorders. Recently, a number of coumarin-based drugs (e.g., coumadin, acenocoumarol, dicoumarol, phenprocoumon, and novobiocin) have been FDA-approved and are in the clinic, and several coumarin-containing compounds are in clinical trials. Our group classified coumarin-based hybrid compounds into groups showing shared biological activities and discussed their potential therapeutic targets.
Açıklama
Anahtar Kelimeler
Coumarin hybrids, Coumarin sulfonamide hybrids, Coumarin-triazole hybrids, Coumarin thiazole hybrids, Coumarin-chalcone hybrids, Coumarin-imidazole hybrids
Kaynak
Medicinal Chemistry Research
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
32
Sayı
4
