Revolution in Cancer Treatment: How Are Intelligently Designed Nanostructures Changing the Game?

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dc.authoridGuel, Desiree/0000-0002-2446-5756
dc.authoridOdabasi, Mehmet/0000-0002-2589-9919
dc.contributor.authorGuel, Desiree
dc.contributor.authorAcet, Burcu Oal
dc.contributor.authorLu, Qiang
dc.contributor.authorStauber, Roland H.
dc.contributor.authorOdabasi, Mehmet
dc.contributor.authorAcet, Omur
dc.date.accessioned2025-03-17T12:25:15Z
dc.date.available2025-03-17T12:25:15Z
dc.date.issued2024
dc.departmentTarsus Üniversitesi
dc.description.abstractNanoparticles (NPs) are extremely important tools to overcome the limitations imposed by therapeutic agents and effectively overcome biological barriers. Smart designed/tuned nanostructures can be extremely effective for cancer treatment. The selection and design of nanostructures and the adjustment of size and surface properties are extremely important, especially for some precision treatments and drug delivery (DD). By designing specific methods, an important era can be opened in the biomedical field for personalized and precise treatment. Here, we focus on advances in the selection and design of nanostructures, as well as on how the structure and shape, size, charge, and surface properties of nanostructures in biological fluids (BFs) can be affected. We discussed the applications of specialized nanostructures in the therapy of head and neck cancer (HNC), which is a difficult and aggressive type of cancer to treat, to give an impetus for novel treatment approaches in this field. We also comprehensively touched on the shortcomings, current trends, and future perspectives when using nanostructures in the treatment of cancer.
dc.description.sponsorshipBrigitte and Dr. Konstanze Wegener Stiftung [90]; Interreg [90] Funding Source: Interreg
dc.description.sponsorshipThe work of D.G. was funded by the Brigitte and Dr. Konstanze Wegener Stiftung (project #90).
dc.identifier.doi10.3390/ijms25105171
dc.identifier.issn1661-6596
dc.identifier.issn1422-0067
dc.identifier.issue10
dc.identifier.pmid38791209
dc.identifier.scopus2-s2.0-85194218814
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3390/ijms25105171
dc.identifier.urihttps://hdl.handle.net/20.500.13099/1580
dc.identifier.volume25
dc.identifier.wosWOS:001232814800001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMdpi
dc.relation.ispartofInternational Journal of Molecular Sciences
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250316
dc.subjectnanoparticle design
dc.subjectcancer
dc.subjecttreatment
dc.subjectnanotheranostics
dc.subjectdrug delivery
dc.titleRevolution in Cancer Treatment: How Are Intelligently Designed Nanostructures Changing the Game?
dc.typeReview

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