Antimicrobial and antioxidant activity of phenolic extracts from walnut (Juglans regia L.) green husk by using pressure-driven membrane process

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dc.authoridArslan, Hudaverdi/0000-0002-3053-6944
dc.contributor.authorArslan, Hudaverdi
dc.contributor.authorKoc, Eda Ondul
dc.contributor.authorOzay, Yasin
dc.contributor.authorCanli, Oltan
dc.contributor.authorOzdemir, Sadin
dc.contributor.authorTollu, Gulsah
dc.contributor.authorDizge, Nadir
dc.date.accessioned2025-03-17T12:27:28Z
dc.date.available2025-03-17T12:27:28Z
dc.date.issued2023
dc.departmentTarsus Üniversitesi
dc.description.abstractIn this study, antioxidant (DPPH and metal chelating), DNA cleavage, biofilm, and antimicrobial properties of extracted phenol from the walnut green husk (WGH) and its different concentrate and permeate samples were evaluated. For maximum phenolic compound extraction from the WGH first, the effects of solvent type (deionized water, methanol, n-hexane, acetone, and ethanol), solvent temperature (25-75 degrees C), and extraction time (0.5-24 h) were optimized. Then to concentrate phenolic compounds a pressure-driven membrane process was used with four different membrane types. The phenol contents of the concentrate samples were found to be microfiltration (MF) concentrate 4400 mg/L, ultrafiltration (UF) concentrate 4175 mg/L, nanofiltration (NF) concentrate 8155 mg/L, and reverse osmosis (RO) concentrate 8100 mg/L. LC-MSMS was used to determine the quantification of phenolic compounds in permeate and concentrate streams. In addition, all of the concentrate samples with high phenol content showed a high antioxidant activity as 100% with MF concentrate, UF concentrate, NF concentrated and RO concentrated. Likewise, concentrate samples were found to have very high antibiofilm activity as 82.86% for NF concentrate againts S. aureus, 85.80% for NF concentrate against P. aureginosa, 80.95% for RO concentrate against S. aureus, and 83.61% for RO-concentrate against P. aureginosa. When the antimicrobial activity of the extracted phenol from WGH and its different concentrate and permeate samples were evaluated by micro dilution and disk diffusion methods, it was found that the ability of the concentrate samples to inhibit bacterial growth was much higher than permeate ones. In addition, extracted phenol from WGH and its different concentrate and permeate samples showed significant DNA nuclease activity.
dc.identifier.doi10.1007/s13197-022-05588-w
dc.identifier.endpage83
dc.identifier.issn0022-1155
dc.identifier.issn0975-8402
dc.identifier.issue1
dc.identifier.pmid36618055
dc.identifier.scopus2-s2.0-85138075737
dc.identifier.scopusqualityQ1
dc.identifier.startpage73
dc.identifier.urihttps://doi.org/10.1007/s13197-022-05588-w
dc.identifier.urihttps://hdl.handle.net/20.500.13099/2280
dc.identifier.volume60
dc.identifier.wosWOS:000854738300003
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer India
dc.relation.ispartofJournal of Food Science and Technology-Mysore
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250316
dc.subjectWalnut green husk
dc.subjectPhenolic compounds extraction
dc.subjectMembrane process
dc.subjectAntioxidant
dc.subjectBiofilm
dc.subjectAntimicrobial
dc.subjectCell viability
dc.subjectDNA cleavage
dc.titleAntimicrobial and antioxidant activity of phenolic extracts from walnut (Juglans regia L.) green husk by using pressure-driven membrane process
dc.typeArticle

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