The Syntheses of Chromium Aluminum Carbide (Cr2AlC) MAX Phase and Cr2CTx MXene and Investigation of Their Antimicrobial Properties

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dc.authoridhttps://orcid.org/0000-0003-2807-0425
dc.authorscopusid5865395550
dc.authorwosidAAM-8078-2020
dc.contributor.authorKaya, Gül
dc.contributor.authorKoç, Eda Ondul
dc.contributor.authorÖzdemir, Sadin
dc.contributor.authorYalçın, M. Serkan
dc.contributor.authorOcakoğlu, Kasım
dc.contributor.authorDizge, Nadir
dc.date.accessioned2024-05-07T12:04:14Z
dc.date.available2024-05-07T12:04:14Z
dc.date.issued2024
dc.departmentFakülteler, Mühendislik Fakültesi, Mühendislik Temel Bilimleri Bölümü
dc.description.abstractChromium aluminum carbide (Cr2AlC) MAX phase and Cr2CTx (MXene-Cr) were synthesized by the pressureless sintering method and hydrothermal method, respectively. In addition to this, the free radical scavenging activities (FRSA) of MAX-Cr phase and MXene-Cr compounds were tested and compared with ascorbic acid and trolox as standard compounds. The obtained FRSA results of MAX-Cr phase and MXene-Cr were 42.82 and 59.64%, respectively, at 100 mg/L concentration. MXene-Cr showed a 66.90% inhibitory effect on ?-amylase at 200 mg/L. The DNA nuclease activity of compounds was determined to be extremely satisfactory at 50, 100, and 200 mg/L concentrations. Moreover, the prepared MAX-Cr phase and MXene-Cr were investigated for antimicrobial activity against six bacterial and two fungal strains by the broth microdilution method. Compounds provided more significant inhibition against Gram-positive bacteria than Gram-negative bacteria and fungi. MAX-Cr phase and MXene-Cr almost completely inhibited microbial cell viability at a 25 mg/L concentration. Additionally, MXene-Cr showed 89.86% and 87.01% antibiofilm activity against S. aureus and P. aeruginosa, respectively, while the antibiofilm activity of the MAX-Cr phase was over 90%.
dc.identifier.citationKaya, G., Koc, E.O., Özdemir, S. Yalçın, M. S.,Ocakoğlu, K. ve Dizge, N. (2024). The Syntheses of Chromium Aluminum Carbide (Cr2AlC) MAX Phase and Cr2CTx MXene and Investigation of Their Antimicrobial Properties. Appl Biochem Biotechnol . https://doi.org/10.1007/s12010-024-04910-w
dc.identifier.doi10.1007/s12010-024-04910-w
dc.identifier.issn0273-2289
dc.identifier.pmid38538871
dc.identifier.scopus2-s2.0-85188820827
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85188820827&doi=10.1007%2fs12010-024-04910-w&partnerID=40&md5=cf7349e5c41cf81f0611acdf524a783d
dc.identifier.urihttps://hdl.handle.net/20.500.13099/225
dc.identifier.wosWOS:001194763400002
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKaya, Gül
dc.institutionauthorOcakoğlu, Kasım
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofApplied Biochemistry and Biotechnology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectAntimicrobial
dc.subjectAntioxidant
dc.subjectBiofilm inhibition
dc.subjectCr2AlC MAX phase (MAX-Cr)
dc.subjectCr2CTx (MXene-Cr)
dc.subjectDNA cleavage
dc.subjectAluminum compounds
dc.subjectAscorbic acid
dc.subjectBacteria
dc.subjectCarbides
dc.subjectChromium compounds
dc.subjectFree radicals
dc.subjectAnti-microbial properties
dc.subjectAntibiofilms
dc.subjectAntimicrobial
dc.subjectBiofilm inhibitions
dc.subjectCr2AlC MAX phase (MAX-cr)
dc.subjectCr2CTx (mxene-cr)
dc.subjectDNA cleavage
dc.subjectFree radical-scavenging activities
dc.subjectMAX-phase
dc.subjectSynthesised
dc.subjectSintering
dc.titleThe Syntheses of Chromium Aluminum Carbide (Cr2AlC) MAX Phase and Cr2CTx MXene and Investigation of Their Antimicrobial Properties
dc.typeArticle

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