The Syntheses of Chromium Aluminum Carbide (Cr2AlC) MAX Phase and Cr2CTx MXene and Investigation of Their Antimicrobial Properties
Yükleniyor...
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/restrictedAccess
Özet
Chromium aluminum carbide (Cr2AlC) MAX phase and Cr2CTx (MXene-Cr) were synthesized by the pressureless sintering method and hydrothermal method, respectively. In addition to this, the free radical scavenging activities (FRSA) of MAX-Cr phase and MXene-Cr compounds were tested and compared with ascorbic acid and trolox as standard compounds. The obtained FRSA results of MAX-Cr phase and MXene-Cr were 42.82 and 59.64%, respectively, at 100 mg/L concentration. MXene-Cr showed a 66.90% inhibitory effect on α-amylase at 200 mg/L. The DNA nuclease activity of compounds was determined to be extremely satisfactory at 50, 100, and 200 mg/L concentrations. Moreover, the prepared MAX-Cr phase and MXene-Cr were investigated for antimicrobial activity against six bacterial and two fungal strains by the broth microdilution method. Compounds provided more significant inhibition against Gram-positive bacteria than Gram-negative bacteria and fungi. MAX-Cr phase and MXene-Cr almost completely inhibited microbial cell viability at a 25 mg/L concentration. Additionally, MXene-Cr showed 89.86% and 87.01% antibiofilm activity against S. aureus and P. aeruginosa, respectively, while the antibiofilm activity of the MAX-Cr phase was over 90%.
Açıklama
Anahtar Kelimeler
Antimicrobial, Antioxidant, Biofilm inhibition, Cr2AlC MAX phase (MAX-Cr), Cr2CTx (MXene-Cr), DNA cleavage, Aluminum compounds, Ascorbic acid, Bacteria, Carbides, Chromium compounds, Free radicals, Anti-microbial properties, Antibiofilms, Antimicrobial, Biofilm inhibitions, Cr2AlC MAX phase (MAX-cr), Cr2CTx (mxene-cr), DNA cleavage, Free radical-scavenging activities, MAX-phase, Synthesised, Sintering
Kaynak
Applied Biochemistry and Biotechnology
WoS Q Değeri
Q2
Scopus Q Değeri
Cilt
Sayı
Künye
Kaya, G., Koc, E.O., Özdemir, S. Yalçın, M. S.,Ocakoğlu, K. ve Dizge, N. (2024). The Syntheses of Chromium Aluminum Carbide (Cr2AlC) MAX Phase and Cr2CTx MXene and Investigation of Their Antimicrobial Properties. Appl Biochem Biotechnol . https://doi.org/10.1007/s12010-024-04910-w
