Subphthalocyanine as a fluorescence imaging agent for breast tumor
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Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Science Bv
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Tri-tert-butyl-carboxyl subphthalocyanine (SubPc) was synthesized and evaluated as a fluorescence agent. Fluorescence imaging for breast tumor in vivo was performed using nude mice as models. Results indicate high uptake in tumor at 20 h. Tumor-non tumor ratio was determined as 2.25. The imaging results demonstrate the potential of this fluorescence-imaging agent in the diagnosis of breast tumor. In the future, subphthalocyanine is also developing as a dual functional, which is fluorescence imaging and as a photodynamic therapeutic agent for the treatment and diagnosis of cancer.
Açıklama
Anahtar Kelimeler
Subphthalocyanine, Fluorescence imaging, Mammary tumor, Nude mice
Kaynak
Photodiagnosis and Photodynamic Therapy
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
26
