Inhibition of bacterial adhesion by epigallocatechin gallate attached polymeric membranes

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dc.authoridDIKICI, EMRAH/0000-0002-3086-8156
dc.authoridPandit, Santosh/0000-0002-8357-758X
dc.authoridMijakovic, Ivan/0000-0002-8860-6853
dc.authoridODABASI, Mehmet/0000-0002-3288-132X
dc.authoridAcet, Omur/0000-0003-1864-5694
dc.contributor.authorAcet, Omur
dc.contributor.authorDikici, Emrah
dc.contributor.authorAcet, Burcu Onal
dc.contributor.authorOdabasi, Mehmet
dc.contributor.authorMijakovic, Ivan
dc.contributor.authorPandit, Santosh
dc.date.accessioned2025-03-17T12:27:24Z
dc.date.available2025-03-17T12:27:24Z
dc.date.issued2023
dc.departmentTarsus Üniversitesi
dc.description.abstractMicrobial adhesion and formation of biofilms cause a serious problem in several areas including but not limited to food spoilage, industrial corrosion and nosocomial infections. These microbial biofilms pose a serious threat to human health since microbial communities in the biofilm matrix are protected with exopolymeric substances and difficult to eradicate with antibiotics. Hence, the prevention of microbial adhesion followed by biofilm formation is one of the promising strategies to prevent these consequences. The attachment of antimicrobial agents, coatings of nanomaterials and synthesis of hybrid materials are widely used approach to develop surfaces having potential to hinder bacterial adhesion and biofilm formation. In this study, epigallocatechin gallate (EGCG) is attached on p(HEMA-co-GMA) membranes to prevent the bacterial colonization. The attachment of EGCG to membranes was proved by Fourier-transform infrared spectroscopy (FT-IR). The synthesized membrane showed porous structure (SEM), and desirable swelling degree, which are ideal when it comes to the application in biotechnology and biomedicine. Furthermore, EGCG attached membrane showed significant potential to prevent the microbial colonization on the surface. The obtained results suggest that EGCG attached polymer could be used as an alternative approach to prevent the microbial colonization on the biomedical surfaces, food processing equipment as well as development of microbial resistant food packaging systems.
dc.description.sponsorshipVetenskapsradet; NordForsk; Independent Research Fund Denmark-FNU [NNF20CC0035580]
dc.description.sponsorshipThis work was supported by Vetenskapsradet to SP, NordForsk, the Independent Research Fund Denmark-FNU and NNF20CC0035580 to IM.
dc.identifier.doi10.1016/j.colsurfb.2022.113024
dc.identifier.issn0927-7765
dc.identifier.issn1873-4367
dc.identifier.pmid36403418
dc.identifier.scopus2-s2.0-85142176186
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.colsurfb.2022.113024
dc.identifier.urihttps://hdl.handle.net/20.500.13099/2215
dc.identifier.volume221
dc.identifier.wosWOS:000891043500001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofColloids and Surfaces B-Biointerfaces
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250316
dc.subjectStaphylococcus aureus
dc.subjectEpigallocatechin gallate
dc.subjectBiofilms
dc.subjectBiomedical device
dc.titleInhibition of bacterial adhesion by epigallocatechin gallate attached polymeric membranes
dc.typeArticle

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