Yildirim, MetinPoyraz, SametErsatir, Mehmet2025-03-172025-03-1720231054-25231554-8120https://doi.org/10.1007/s00044-023-03025-xhttps://hdl.handle.net/20.500.13099/2381Coumarin hybrids have been designed and synthesized as an important new strategy in the field of medicinal chemistry. Coumarin core has been shown to form various compounds to combat several diseases including microbial, cancer, inflammatory, and neurodegenerative disorders. Recently, a number of coumarin-based drugs (e.g., coumadin, acenocoumarol, dicoumarol, phenprocoumon, and novobiocin) have been FDA-approved and are in the clinic, and several coumarin-containing compounds are in clinical trials. Our group classified coumarin-based hybrid compounds into groups showing shared biological activities and discussed their potential therapeutic targets.eninfo:eu-repo/semantics/closedAccessCoumarin hybridsCoumarin sulfonamide hybridsCoumarin-triazole hybridsCoumarin thiazole hybridsCoumarin-chalcone hybridsCoumarin-imidazole hybridsReview10.1007/s00044-023-03025-x324617642Q3WOS:0009319614000012-s2.0-85147682576Q1