Tuncel, AycaOzturk, IsmailInce, MineOcakoglu, KasimHosgor-Limoncu, MineYurt, Fatma2025-03-172025-03-1720191088-42461099-1409https://doi.org/10.1142/S1088424619500238https://hdl.handle.net/20.500.13099/1756Antibiotic resistance is an increasing healthcare problem worldwide. In the present study, the effects of antimicrobial photodynamic therapy (APDT) of ZnPc and ZnPc-integrated TiO2 nanoparticles (ZnPc-TiO2) were investigated against Staphylococcus aureus. A light emitting diode (LED) (630-700 nm, 17.4 mW/cm(2)) was used on S. aureus at different light doses (8 J/cm(2) for 11 min, 16 J/cm(2) for 22 min, 24 J/cm(2) for 33 min) in the presence of the compounds under the minimum inhibitory concentration values. Both compounds showed similar phototoxicity toward S. aureus when high light doses (16 and 24 J/cm(2)) were applied. In addition, the success of APDT increased with an increasing light dose.eninfo:eu-repo/semantics/closedAccessantimicrobial photodynamic therapy (APDT)phthalocyanine (Pc)TiO2 nanoparticlesStaphylococcus aureusArticle10.1142/S1088424619500238231-2206212Q4WOS:0004604673000222-s2.0-85061988073Q3