Shinde, Vikas B.Mhaldar, Pradeep M.Patil, Mayuri V.Mirzaei, MahmoudPore, Dattaprasad M.2025-03-172025-03-1720242365-6549https://doi.org/10.1002/slct.202303989https://hdl.handle.net/20.500.13099/2388In present study we have designed and synthesized novel cellulose supported ionic liquid catalyst (CSILC), [Cell@Al2O3(HEPiPY)]DCA and explored its catalytic efficiency for synthesis of novel 11b,12-dihydro-6H,13Hbenzo[5,6][1,3]oxazino[3,4-a]quinazoline-6,13-diones by performing the one pot reaction of 2-(2-hydroxyaryl)-2,3- dihydroquinazolin-4(1H)-one and 1,1-carbonyl diimidazole (CDI). The catalyst was characterized by diverse analytical techniques viz. Fourier-Transform Infrared Spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), Energy Dispersive X-ray Analysis (EDX) and Thermo Gravimetric Analysis (TGA). The biological activities of synthesized novel derivatives were evaluated along with in silico assessments against the vascular endothelial growth factor receptor-2 (VEGFR-2) target, in which the results were considerable. The catalyst exhibited remarkable reusability up to six consecutive runs without considerable loss in the catalytic activity.eninfo:eu-repo/semantics/closedAccess1,1-carbonyldiimidazoleCelluloseCyclizationIonic liquidsMolecular dockingOxazinoquinazolineArticle10.1002/slct.20230398994Q3WOS:0011550886000012-s2.0-85182840567Q3