Identification and Assessment of Therapeutic Phytoconstituents of Catharanthus roseus through GC-MS Analysis

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dc.authoridKAPOOR, MANISH/0000-0002-8349-8910
dc.authoridDhull, Sanju Bala/0000-0002-5749-6241
dc.authoridJuric, Slaven/0000-0002-5443-8927
dc.authoridRani, Jyoti/0000-0001-6334-4642
dc.authoridGoksen, Gulden/0000-0002-5432-7936
dc.contributor.authorRani, Jyoti
dc.contributor.authorKapoor, Manish
dc.contributor.authorDhull, Sanju Bala
dc.contributor.authorGoksen, Gulden
dc.contributor.authorJuric, Slaven
dc.date.accessioned2025-03-17T12:25:13Z
dc.date.available2025-03-17T12:25:13Z
dc.date.issued2023
dc.departmentTarsus Üniversitesi
dc.description.abstractThe leaves of Catharanthus roseus (L.) G. Don contain a large number of diverse secondary metabolites, making them comparably complex. The Catharanthus genus has received increased interest from scientists in recent years due to its extensive applications in several domains, including the pharmaceutical sector, where precise characterization of its characteristics is required. An effective inquiry technique is needed for chemo-profiling to identify the metabolites in plant samples. The main goal of this research is to provide supplementary data on the chemical composition of the leaves of twenty-five different accessions of C. roseus through the application of gas chromatography-mass spectrometry (GC-MS). The study's findings reveal the existence of a vast number of phytochemicals, allowing for a comparison of the different accessions. Furthermore, a meticulous statistical analysis of this data using principal components analysis (PCA) and a heatmap, and hierarchical cluster analysis (HCA) may aid in providing more relevant information on C. roseus leaves for possible investigation of their metabolites in further scientific studies.
dc.identifier.doi10.3390/separations10060340
dc.identifier.issn2297-8739
dc.identifier.issue6
dc.identifier.scopus2-s2.0-85163785044
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.3390/separations10060340
dc.identifier.urihttps://hdl.handle.net/20.500.13099/1559
dc.identifier.volume10
dc.identifier.wosWOS:001015826800001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherMdpi
dc.relation.ispartofSeparations
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250316
dc.subjectCatharanthus roseus
dc.subjectgas chromatography-mass spectrophotometry
dc.subjectphytochemicals
dc.subjectprincipal component analysis
dc.subjecthierarchical cluster analysis (HCA)
dc.titleIdentification and Assessment of Therapeutic Phytoconstituents of Catharanthus roseus through GC-MS Analysis
dc.typeArticle

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