Optimization Studies of Cryogel Scaffolds Prepared Using Different Chitosan and Polyvinyl Alcohol Ratios

dc.contributor.authorGül, Gülşah
dc.contributor.authorDemir, Didem
dc.contributor.authorBolgen, Nimet
dc.date.accessioned2025-03-17T12:19:52Z
dc.date.available2025-03-17T12:19:52Z
dc.date.issued2023
dc.departmentTarsus Üniversitesi
dc.description.abstractCryogels are scaffolds structured with interconnected porous matrices produced from frozen solutions of monomeric or polymeric initiators. These scaffolds are seen as unique candidates with desirable properties for the different biomedical fields including tissue engineering, wound dressing, and drug delivery systems. In this study, polyvinyl alcohol (PVA) and chitosan (CS) were used to fabricate PVA:CS composite cryogels. Cryogels prepared at different polymer ratios were evaluated in terms of chemical structure, morphology, porosity, and swelling ratio. The chemical structure of composite cryogels was determined using Fourier-transform infrared spectroscopy (FTIR). The interconnected pore morphology was observed using Scanning Electron Microscopy (SEM). Porosity and swelling ratio values were determined based on the weight change of the cryogels. In general, all samples exhibited a porous structure, and it was revealed that porosity and other properties differ according to the ratio of each polymer in the scaffolds.
dc.identifier.endpage1121
dc.identifier.issn2687-3729
dc.identifier.issue2
dc.identifier.startpage1110
dc.identifier.trdizinid1205225
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1205225
dc.identifier.urihttps://hdl.handle.net/20.500.13099/1220
dc.identifier.volume6
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofOsmaniye Korkut Ata Üniversitesi Fen Bilimleri Enstitüsü Dergisi (Online)
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TR_20250316
dc.subjectTissue engineering
dc.subjectcryogel
dc.subjectchitosan
dc.subjectscaffold
dc.subjectpolyvinyl alcohol
dc.titleOptimization Studies of Cryogel Scaffolds Prepared Using Different Chitosan and Polyvinyl Alcohol Ratios
dc.typeArticle

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