Advancing antimicrobial efficacy of Cucumis momordica seeds: Nanoemulsion application in Eurotium cristatum-mediated solid-state fermentation

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dc.authorid, Maharshi Bhaswant/0000-0003-4501-5487
dc.authoridALI, NEMAT/0000-0001-6525-4202
dc.contributor.authorSharma, Madhu
dc.contributor.authorGoksen, Gulden
dc.contributor.authorAli, Nemat
dc.contributor.authorJanghu, Sandeep
dc.contributor.authorParvez, Mohammad Khalid
dc.contributor.authorAl-Dosari, Mohammed S.
dc.contributor.authorBhaswant, Maharshi
dc.date.accessioned2025-03-17T12:27:16Z
dc.date.available2025-03-17T12:27:16Z
dc.date.issued2024
dc.departmentTarsus Üniversitesi
dc.description.abstractThis study explores the enhancement of Cucumis momordica seed powder's properties through Eurotium cristatummediated solid-state fermentation (SSF) and its application in nanoemulsions, emphasizing protein content, functional properties, stability, and antimicrobial activity. The protein content increased significantly from 23.28 +0.23 % in the control to 29.83+0.12 % after 144 h of fermentation. The Cucumis momordica seed powder fermented for 96 h was further analyzed for its functional properties and characterization. The water absorption capacity was increased from 0.91 to 2.56 g/g, and oil absorption capacity from 0.79 to 1.16 g/g. SEM and FTIR analyses revealed morphological changes and chemical profile alterations, indicating enzymatic degradation and enhanced functional properties. Nanoemulsions from fermented powder showed reduced droplet sizes (148 +0.34 nm to 126+0.37 nm) and more negative zeta potentials (-24.5+0.12 mV to -25.79+0.18 mV), suggesting improved stability. Temperature stability was superior in fermented seed powder nanoemulsions, demonstrating enhanced thermal resistance. Antimicrobial tests against E. coli and S. aureus showed significantly lower MIC and MBC values for fermented powder nanoemulsions (E. coli MIC: 1.089 mg/mL, MBC: 2.189 mg/mL; S. aureus MIC: 0.459 mg/mL, MBC: 1.196 mg/mL), indicating increased antimicrobial efficacy. These results highlight the potential of SSF and nanoemulsion technology in advancing the functionality and application of Cucumis Momordica seeds as natural antimicrobial agents.
dc.description.sponsorshipKing Saud University, Riyadh, Saudi Arabia [RSP2024R379]
dc.description.sponsorshipThe authors are thankful to the Researchers Supporting Project Number (RSP2024R379) , King Saud University, Riyadh, Saudi Arabia for supporting this study.
dc.identifier.doi10.1016/j.fbp.2024.10.008
dc.identifier.endpage518
dc.identifier.issn0960-3085
dc.identifier.issn1744-3571
dc.identifier.scopus2-s2.0-85207354496
dc.identifier.scopusqualityQ1
dc.identifier.startpage507
dc.identifier.urihttps://doi.org/10.1016/j.fbp.2024.10.008
dc.identifier.urihttps://hdl.handle.net/20.500.13099/2167
dc.identifier.volume148
dc.identifier.wosWOS:001369477500001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofFood and Bioproducts Processing
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250316
dc.subjectCucumis momordica seeds
dc.subjectEurotium cristatum
dc.subjectSolid-state fermentation
dc.subjectNanoemulsion
dc.subjectAntimicrobial agent
dc.titleAdvancing antimicrobial efficacy of Cucumis momordica seeds: Nanoemulsion application in Eurotium cristatum-mediated solid-state fermentation
dc.typeArticle

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