Antimicrobial activity enhancement of PVA/chitosan films with the additive of CZTS quantum dots

Basit Öğe Kaydı
dc.authoridhttps://orcid.org/0000-0003-2807-0425en_US
dc.authoridhttps://orcid.org/0000-0001-7432-7725en_US
dc.authoridhttps://orcid.org/0000-0002-2977-2077en_US
dc.authorscopusid55820407700en_US
dc.authorscopusid36088420200en_US
dc.authorscopusid57218339719en_US
dc.authorwosidAAM-8078-2020en_US
dc.authorwosidIYS-7709-2023en_US
dc.authorwosidIVV-2642-2023en_US
dc.contributor.authorCeylan, Seda
dc.contributor.authorKüçükosman, Rıdvan
dc.contributor.authorYurt, Fatma
dc.contributor.authorÖzel, Derya
dc.contributor.authorÖztürk, İsmail
dc.contributor.authorDemir, Didem
dc.contributor.authorOcakoğlu, Kasım
dc.date.accessioned2024-08-19T11:48:33Z
dc.date.available2024-08-19T11:48:33Z
dc.date.issued2023en_US
dc.departmentFakülteler, Mühendislik Fakültesi, Mühendislik Temel Bilimleri Bölümüen_US
dc.description.abstractThe wound environment is a breeding ground for pathogens, and traditional wound dressing materials lack antibacterial properties. In this work, we aimed to develop PVA/chitosan (P/C)-based wound dressing scaffolds with anti-infective properties using Cu2ZnSnS4 quantum dots (CZTS QDs) to prevent infections in the wound. CZTS quantum dots were prepared by a simple hydrothermal process and characterized using appropriate techniques such as TEM, XRD, FTIR spectrum, and UV-Vis absorption spectroscopy. CZTS QDs were subsequently loaded at different concentrations onto PVA/chitosan membranes (0, 1.6, 2.5 and 3.3% w/w, based on the total polymer quantity). The chemical structure, contact angle and mechanical properties of the membranes were analyzed, and their antimicrobial activities and cell viability were also investigated. The cytocompatibility of the membranes and cell morphology was investigated using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and SEM. Based on studies on the interactions between membranes and cells, it was determined that incorporation of CZTS QDs into the membrane did not cause toxicity. To the best of our knowledge, this is the first report on loading CZTS QDs into membranes for tissue engineering applications, and the overall findings suggest that CZTS QDs-integrated membranes might have potentially appealing uses as antimicrobial films for wound healing.en_US
dc.identifier.citationCeylan, S., Küçükosman, R., Yurt, F., Özel, D., Öztürk, İ. Demir, D. ve Ocakoğlu, K. (2023). Antimicrobial activity enhancement of PVA/chitosan films with the additive of CZTS quantum dots. Polymer Bulletin, 80 (10), 11273–11293. Erişim adresi:https://doi.org/10.1007/s00289-022-04615-2en_US
dc.identifier.doi10.1007/s00289-022-04615-2en_US
dc.identifier.endpage11293en_US
dc.identifier.issn0170-0839
dc.identifier.issn1436-2449
dc.identifier.issue10en_US
dc.identifier.scopus2-s2.0-85142938628en_US
dc.identifier.startpage11273en_US
dc.identifier.urihttps://doi.org/10.1007/s00289-022-04615-2
dc.identifier.urihttps://hdl.handle.net/20.500.13099/360
dc.identifier.volume80en_US
dc.identifier.wos000892917600001en_US
dc.identifier.wosqualityQ2en_US
dc.institutionauthorOcakoğlu, Kasım
dc.institutionauthorKüçükosman, Rıdvan
dc.institutionauthorDemir, Didem
dc.language.isoengen_US
dc.publisherSpringer Linken_US
dc.relation.ispartofPolymer Bulletinen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/restrictedAccessen_US
dc.subjectCu2ZnSnS4 quantum dotsen_US
dc.subjectCZTSen_US
dc.subjectChitosanen_US
dc.subjectPVAen_US
dc.subjectAbsorption spectroscopyen_US
dc.subjectBiomechanicsen_US
dc.subjectChemical analysisen_US
dc.subjectContact angleen_US
dc.subjectCopper compoundsen_US
dc.subjectFourier transform infrared spectroscopyen_US
dc.subjectMembranesen_US
dc.subjectNanocrystalsen_US
dc.subjectTin compoundsen_US
dc.subjectZinc compoundsen_US
dc.subjectActivity enhancementen_US
dc.subjectAnti-microbial activityen_US
dc.subjectAntibacterial propertiesen_US
dc.subjectBreeding groundsen_US
dc.subjectChitosan filmen_US
dc.subjectCu2ZnSnS4 quantum doten_US
dc.subjectWound dressing materialsen_US
dc.subjectWound dressingsen_US
dc.titleAntimicrobial activity enhancement of PVA/chitosan films with the additive of CZTS quantum dotsen_US
dc.typearticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
2024-08-19 151952.png
Boyut:
185.15 KB
Biçim:
Portable Network Graphics
Açıklama:
Makale Dosyası
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Mühendislik Fakültesi Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu