Antimicrobial photodynamic therapy against Staphylococcus aureus using zinc phthalocyanine and zinc phthalocyanine integrated TiO2 nanoparticles
[ X ]
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
World Scientific Publ Co Pte Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Antibiotic resistance is an increasing healthcare problem worldwide. In the present study, the effects of antimicrobial photodynamic therapy (APDT) of ZnPc and ZnPc-integrated TiO2 nanoparticles (ZnPc-TiO2) were investigated against Staphylococcus aureus. A light emitting diode (LED) (630-700 nm, 17.4 mW/cm(2)) was used on S. aureus at different light doses (8 J/cm(2) for 11 min, 16 J/cm(2) for 22 min, 24 J/cm(2) for 33 min) in the presence of the compounds under the minimum inhibitory concentration values. Both compounds showed similar phototoxicity toward S. aureus when high light doses (16 and 24 J/cm(2)) were applied. In addition, the success of APDT increased with an increasing light dose.
Açıklama
Anahtar Kelimeler
antimicrobial photodynamic therapy (APDT), phthalocyanine (Pc), TiO2 nanoparticles, Staphylococcus aureus
Kaynak
Journal of Porphyrins and Phthalocyanines
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
23
Sayı
1-2
