Antimicrobial photodynamic therapy against Staphylococcus Aureus using zinc phthalocyanine and zinc phthalocyanineintegrated TiO2 nanoparticles
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Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
World Scientific Publishing Co.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Antibiotic resistance is an increasing healthcare problem worldwide. In the present study, the effects of antimicrobial photodynamic therapy (APDT) of ZnPc and ZnPc-integrated TiO2 nanoparticles (ZnPc-TiO2) were investigated against Staphylococcus aureus. A light emitting diode (LED) (630-700 nm, 17.4 mW/cm2) was used on S. aureus at different light doses (8 J/cm2 for 11 min, 16 J/cm2 for 22 min, 24 J/cm2 for 33 min) in the presence of the compounds under the minimum inhibitory concentration values. Both compounds showed similar phototoxicity toward S. aureus when high light doses (16 and 24 J/cm2) were applied. In addition, the success of APDT increased with an increasing light dose. © 2021 by World Scientific Publishing Co. Pte. Ltd.
Açıklama
Anahtar Kelimeler
antimicrobial photodynamic therapy (APDT), Phthalocyanine (PC), Staphylococcus aureus, Tio<sub>2</sub> nanoparticles
Kaynak
Porphyrin Science By Women (In 3 Volumes)
WoS Q Değeri
Scopus Q Değeri
N/A
