Validity and reliability of the Turkish version of the Canadian Haemophilia Outcomes-Kids’ Life Assessment Tool (The CHO-KLAT)

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dc.contributor.authorTat, Ayşe Merve
dc.contributor.authorTat, Necati Muhammed
dc.contributor.authorKaraman, Kamuran
dc.contributor.authorÖner, Ahmet Fayik
dc.contributor.authorGönen, Tuğba
dc.contributor.authorAkbayram, Sinan
dc.contributor.authorDeniz, Volkan
dc.date.accessioned2025-03-17T12:22:56Z
dc.date.available2025-03-17T12:22:56Z
dc.date.issued2024
dc.departmentTarsus Üniversitesi
dc.description.abstractObjective: The evaluation of health-related quality of life (HRQoL) is encouraged to assess the multidimensional impact of treatments and disease and to improve care in boys with hemophilia (BwH). However, validated HRQoL tools for BwH are not yet available for Turkish. The purpose of this study was to assess the validity and reliability of the Canadian Hemophilia Outcomes-Kids’ Life Assessment Tool (CHO-KLAT), version 2.0, which is multilingual valid tool, in Turkish. Methods: The procedure included 4 steps: linguistic translation, content validity, validity evaluation with the Pediatric Quality of Life (PedsQL), finally test-retest analysis for reliability assessment. The participants were questioned for the type and severity of hemophilia, medical treatment, and inhibitor status. Results: The primary Turkish version of the CHO-KLAT evolved with the cooperation of the Canadian and Turkish teams. Content validity was performed with 9 experts and latest version of Turkish CHO-KLAT was produced. This multicenter study was conducted with 53 BwH aged 4-18 for validity assessment, 52 BwH for test-retest reliability. The mean age of BwH was 11.6 (standard deviation (SD): 4.2). The means of CHO-KLAT and PedsQL were 64.1 (SD: 4.2) and 66.7 (SD: 15.3). As a result of the validity evaluation, a strong correlation was found between CHO-KLAT and PedsQL (r = 0.603; P < .001). The interclass correlation coefficient was 0.887 in the test-retest reliability. Conclusion: The Turkish version of CHO-KLAT 2.0 was validated. It is now available to be used in clinical studies for HRQoL assessment of Turkish BwH. © 2024 AVES. All rights reserved.
dc.identifier.doi10.5152/ArcHealthSciRes.2024.23069
dc.identifier.endpage132
dc.identifier.issn2687-4644
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85196786571
dc.identifier.scopusqualityQ4
dc.identifier.startpage128
dc.identifier.trdizinid1273132
dc.identifier.urihttps://doi.org/10.5152/ArcHealthSciRes.2024.23069
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1273132
dc.identifier.urihttps://hdl.handle.net/20.500.13099/1486
dc.identifier.volume11
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherAVES
dc.relation.ispartofArchives of Health Science and Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_Scopus_20250316
dc.subjectchildren
dc.subjectHemophilia
dc.subjectquality of life
dc.subjectreliability
dc.subjectvalidity
dc.titleValidity and reliability of the Turkish version of the Canadian Haemophilia Outcomes-Kids’ Life Assessment Tool (The CHO-KLAT)
dc.typeArticle

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