Yazar "Vaseashta, Ashok" seçeneğine göre listele

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    Electrospun Nanofibers for Biomedical, Sensing, and Energy Harvesting Functions
    (Mdpi, 2023) Demir, Didem; Bolgen, Nimet; Vaseashta, Ashok
    The process of electrospinning is over a century old, yet novel material and method achievements, and later the addition of nanomaterials in polymeric solutions, have spurred a significant increase in research innovations with several unique applications. Significant improvements have been achieved in the development of electrospun nanofibrous matrices, which include tailoring compositions of polymers with active agents, surface functionalization with nanoparticles, and encapsulation of functional materials within the nanofibers. Recently, sequentially combining fabrication of nanofibers with 3D printing was reported by our group and the synergistic process offers fiber membrane functionalities having the mechanical strength offered by 3D printed scaffolds. Recent developments in electrospun nanofibers are enumerated here with special emphasis on biomedical technologies, chemical and biological sensing, and energy harvesting aspects in the context of e-textile and tactile sensing. Energy harvesting offers significant advantages in many applications, such as biomedical technologies and critical infrastructure protection by using the concept of finite state machines and edge computing. Many other uses of devices using electrospun nanofibers, either as standalone or conjoined with 3D printed materials, are envisaged. The focus of this review is to highlight selected novel applications in biomedical technologies, chem.-bio sensing, and broadly in energy harvesting for use in internet of things (IoT) devices. The article concludes with a brief projection of the future direction of electrospun nanofibers, limitations, and how synergetic combination of the two processes will open pathways for future discoveries.
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    Hierarchical Integration of 3D Printing and Electrospinning of Nanofibers for Rapid Prototyping
    (Springer International Publishing, 2022) Vaseashta, Ashok; Demir, Didem; Sakım, Burcu; A Ş Ik, Müge; Bölgen, Nimet
    Electrospinning is an effective and versatile technique used to produce porous structures ranging from submicron to nanometer diameters. Using a variety of high-performance polymers and blends, several porous structure configurations have become possible for applications in tactile sensing, energy harvesting, filtration, and biomedical applications, however, the structures lack mechanical complexity, conformity, and desired three-dimensional single/multi-material constructs necessary to mimic desired structures. A simple, yet versatile, strategy is through employing digitally-controlled fabrication of shape-morphing by combining two promising technologies, viz., electrospinning and 3D printing/additive manufacturing. Using hierarchical integration of configurations, elaborate shapes and patterns are printed on mesostructured stimuli-responsive electrospun membranes, modulating in-plane and interlayer internal stresses induced by swelling/shrinkage mismatch, and thus guiding morphing behaviors of electrospun membranes to adapt to changes of the environment. Recent progress in 3D/4D printing/additive manufacturing processes includes materials and scaffold constructs for tactile and wearable sensors, filtration structures, sensors for structural health monitoring, biomedical scaffolds, tissue engineering, and optical patterning, among many other applications to support the vision of synthetically prepared material systems that mimic many of the structural aspects with digital precision.Anovel technology called 3Djet writingwas recently reported that catapults electrospinning to adaptive technologies for the manufacturing of scaffolds according to user-defined specifications of the shape and size of both the pores and the overall geometric footprint. This chapter reviews the hierarchical synergy between electrospinning and 3D printing as part of precision micromanufacturing for rapid prototyping of structures that are likely to evolve next-generation structures into reality. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.
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    Integrating 3D Printing and Electrospinning to Fabricate Scaffolds for Bone Regeneration
    (CRC Press, 2024) Demir, Didem; Vaseashta, Ashok; Bölgen, Nimet
    Bone tissue engineering (BTE) aims to induce tissue regeneration through synergizing scaffolds, cells, and growth factors. As the main component of BTE, scaffolds produced traditionally using particulate leaching and solvent casting, freeze-drying, electrospinning, 3D printing/additive manufacturing, and phase separation should ideally mimic the natural structure of bone by exhibiting certain biological, mechanical, physical, and chemical properties. Moreover, traditional techniques should be manipulated or combined with modern technologies to provide the desired physicochemical properties. Among the traditional manufacturing methodologies, electrospinning and 3D printing produce materials with a wide variety of applications due to their unique properties. Therefore, combining these two techniques is an important breakthrough in improving the final properties of scaffolds: The 3D printing makes it possible to construct scaffolds that will fill complex bone defects, while electrospinning produces micro- and nanostructured fibers that provide a suitable microenvironment for regenerating and facilitating bone. First, we present information about the general principles, concepts, and applications of BTE. Then, we introduce modified methods and BTE applications of hybrid systems involving both 3D printing and electrospinning. Finally, we summarize the future direction, the issues that need to be improved or developed, and the surrounding challenges. © 2025 selection and editorial matter, Ashok Kumar, Sneha Singh, and Prerna Singh; individual chapters, the contributors.
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    Introduction and Fundamentals of Electrospinning
    (Springer International Publishing, 2022) Bölgen, Nimet; Demir, Didem; Aşık, Müge; Sakım, Burcu; Vaseashta, Ashok
    Electrospinning is an effective and versatile technique used to produce continuous fibers from submicron down to nanometer diameters. The produced nanofibers from polymer solutions or melts have been a focus of interest as they have many potential applications in energy conversion and storage, environmental, biomedical, and pharmacological area. In addition, new application areas are created by functionalizing the produced nanofibers with different features as antimicrobial, conductive, responsive to stimulus, and biomimetic properties. Conventional electrospinning setup can be modified for large-scale and continuous production by integration with developing technologies. In this chapter, firstly, history, process theory, and basic principles of electrospinning are summarized. Then, the latest developed technologies related to electrospinning, functionalization routes to add superior features to the nanofibrous materials, and remarkable application areas of electrospun nanofibers are presented. Finally, future trends in the electrospinning area are discussed. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.
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    Synergetic Integration of Electrospinning and Additive 3D/4D Printing Process for Biomedical Applications
    (Springer Science and Business Media Deutschland GmbH, 2023) Vaseashta, Ashok; Demir, Didem; Bolgen, Nimet
    Electrospinning is a versatile technique and has been used to produce porous fibers ranging from submicron to nanometer in diameter. Using a variety of high-performance polymers and blends, several new configurations are, now, possible for applications in tactile sensing, energy harvesting, filtration, and biomedical technologies. The structures, however, lack desired mechanical conformity, complexity, and single/multi-material three-dimensional rigid constructs essential to mimic specific functionalities. A simple, yet versatile, strategy is by employing a digitally controlled fabrication process of shape-morphing called 3D printing/additive manufacturing process and by conjoining the two promising technologies. Thus, using strategic and hierarchical integration of processes, elaborate shapes, and patterns can be fabricated on mesostructured stimuli-responsive electrospun membranes. The focus of this investigation is primarily on biomedical structures, as part of a large effort of precision and advanced manufacturing for rapid prototyping. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2023.