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    A comprehensive review of the bioactive components of sesame seeds and their impact on bone health issues in postmenopausal women
    (Royal Soc Chemistry, 2023) Arooj, Ammara; Rabail, Roshina; Naeem, Muhammad; Goksen, Gulden; Xu, Baojun; Aadil, Rana Muhammad
    Sesame seeds perform many therapeutic functions against several health issues especially those related to bones because they possess a rich content of calcium, vitamins, proteins, oil, and carbohydrates. Using the PubMed, ScienceDirect, and Google Scholar databases, we performed a comprehensive search of the literature from 2013 to date on reports related to sesame seeds and their bioactive ingredients. Sesamin, sesamol, sesamolin, and sesamol are the major bioactive lignans found in sesame seeds. Our comprehensive review of the literature revealed the protective role of sesame seeds towards bone health in postmenopausal osteoporosis. It was observed that sesame seeds have a positive impact on postmenopausal women experiencing bone-related problems, i.e. osteoporosis and arthritis. Therefore, this review is focused on exploring the effect of sesame seeds on bone mineralization in women experiencing menopause. Furthermore, to aid balancing the hormones in women after their disturbance by the postmenopausal phase, we highlight the effect of the daily intake of sesame seeds in women. Finally, we conclude that the supplementation of sesame seeds in a regular diet shows a positive impact on the bone health of post-menopausal osteoporosis.
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    An insight into anticancer perspectives of chickpea bioactive compounds
    (Elsevier Ltd, 2023) Sehar, Sabrina; Rabail, Roshina; Munir, Seemal; Shakeel, Khunsha; Khalil, Anees Ahmed; Tufail, Tabussam; Abid, Muhammad
    Cancers of the lung, colon, liver, stomach, and breast are common worldwide and have significant fatality rates. Cachexia caused by cancer is the major cause of death in cancer patients, and malnutrition and metabolic illnesses have become more widespread in recent years. To combat these health conditions, proper nutrition is essential. Chickpeas include a variety of bioactive components, including antioxidants, phytochemicals, and bioactive peptides, all of which have preventative and protective health effects. This review summarizes the evidence-based studies on chickpeas’ ability to serve as a valuable source of bioactive chemicals that can help protect against many types of cancer. Chickpeas include secondary metabolites including quercetin and myricetin, as well as phenolic acids and vitamins A, B, and E, which may protect the body from free radicals. Chickpeas have the highest total phenolic content and essential amino acid concentration of any germinated seed. Chickpea storage proteins, such as globulins, glutelins, albumins, and prolamins, are high in protein and can help with cachexia. These proteins contain angiotensin-converting enzyme inhibitory and anti-proliferative capabilities, making them useful in the treatment of a wide range of cancers. As a result, this article provides advice to consumers on improving their eating habits to protect against and fight cancer and may serve as a foundation for future clinical studies. © 2023 The Author(s)