Yazar "Khan, Mohammad Rashid" seçeneğine göre listele

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    Biomass-derived carbon quantum dots from C hlorella vulgaris: Photocatalytic reduction of malachite green dye coupled with anti-quorum sensing and antimicrobial activity against food pathogens
    (Elsevier, 2024) Thakur, Sweezee; Bains, Aarti; Kumar, Anil; Goksen, Gulden; Dhull, Sanju Bala; Ali, Nemat; Khan, Mohammad Rashid
    Algae, particularly Chlorella vulgaris, , present a novel, sustainable source for producing carbon quantum dots (CQDs) with unique properties. This study introduces an eco-friendly synthesis method using a hydrothermal process at 200 degrees C for 12 h, yielding stable, spherical CQDs with an average diameter of 7.19 +/- 0.06 nm, composed primarily of carbon and oxygen. The innovation consists on employing microalgal biomass for the production of CQDs, hence obviating the necessity for additional chemicals or passivating agents. The CQDs exhibit a fluorescence peak at 416 nm upon excitation at 241 nm, with UV-visible spectra showing pi ->pi* and n ->pi* transition at 241 nm and 356 nm, respectively. High-resolution TEM analysis reveals a crystalline structure with a 0.21 nm interlayer spacing, confirmed by lattice fringes, and a quantum yield of 41.24%, indicating efficient photoluminescence. The CQDs demonstrate strong antimicrobial activity against pathogens like Staphylococcus aureus and Pseudomonas aeruginosa, , with significant inhibition of quorum sensing like twitching and swarming and bacterial motilities. Furthermore, the CQDs achieve a 91.47% degradation of malachite green dye, underscoring their potential in environmental remediation. This study highlights the dual applications of Chlorella vulgaris-derived CQDs in health and environmental contexts, presenting a sustainable and innovative approach for nanomaterial synthesis.
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    Exploration of Agrocybe aegerita mushroom polysaccharide-polyphenolic complex: Functional properties, binding efficiency, and biological activities
    (Elsevier, 2025) Bains, Aarti; Goksen, Gulden; Ali, Nemat; Khan, Mohammad Rashid; Patil, Sandip; Chawla, Prince
    This study investigates the functional and biological activities of a polysaccharide-polyphenolic complex derived from the edible mushroom Agrocybe aegerita. Polyphenols were extracted using a modified solvent evaporation technique, and polysaccharides (AMP) were extracted using enzyme-assisted methods, yielding 8.02 %. The presence of fructose, mannose, glucose, galactose, sucrose, and maltose in varying amounts was confirmed. Different mushroom extracts concentrations (0.025-1.00 %) were tested for interaction with AMP. Samples with 0.2 % and 0.5 % extracts showed significantly higher binding efficiency with polysaccharides. AMP exhibited a particle size of 319 nm, while mushroom polysaccharide-polyphenolic compound complex (AMPP) revealed 136 nm with an irregular shape and smooth surface. Both AMP and AMPP showed three stages of decomposition, with distinct weight loss. Anti-quorum sensing tests against P. aeruginosa PAO1 showed that AMPP significantly decreased pyocyanin, pyoverdine, and swarming activity and exhibited higher biofilm inhibition. These findings suggest that the AMPP has substantial potential for developing sustainable health products, owing to its enhanced bioactivity.
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    Öğe
    Optimization of ultrasonication assisted extraction of Aegle marmelos fruit shell nano polysaccharide and evaluation of photocatalytic dye reduction and edible coating for fresh-cut fruits
    (Elsevier, 2024) Sharma, Madhu; Bains, Aarti; Goksen, Gulden; Ali, Nemat; Khan, Mohammad Rashid; Karabulut, Gulsah; Chawla, Prince
    Aegle marmelos (AM) fruit shell, considered waste, is an excellent source of bioactive compounds, including polysaccharides. Therefore, this study focuses on the extraction of AM polysaccharides using an ultrasonicationassisted approach. Different parameters, including ultrasonic power (200-600 W), time (5-15 min), and solid-tosolvent ratio (10-20 mg/mL), were employed, and significantly (p < 0.05) higher yield (16.93 %) was achieved at 400 W for 10 min. Monosaccharides composition revealed galactose (30.56 +/- 0.76 %), galacturonic acid (24.72 +/- 0.12 %), arabinose (17.26 +/- 0.35 %), xylose (11.48 +/- 0.21 %), glucose (10.52 +/- 0.26 %), and rhamnose (5.39 +/- 0.67 %), which were then confirmed by C-13 spectrum. AM polysaccharides revealed nanoscale size with excellent structural crystallinity and thermal stability. Edible coatings of varying concentrations (0.5-2 %) were formulated and optimized 1 % coating, demonstrating efficacy in mitigating weight loss, microbial proliferation, and browning in cut apples. As well, AM polysaccharides prominently degraded 82.79 +/- 0.39 % of methyl green. Overall, bael shells as a valuable source of polysaccharides, offering the potential for both photocatalytic dye degradation and food preservation.